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A Study of Stereotactic Radiosurgery (SRS) in People With Brain Cancer Having Tumor Resection Surgery

StatusRecruiting
PhaseNot applicable
Started2026-08-28
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary endpoint reworded 1 of 1 changed
See other at-risk trials from Memorial Sloan Kettering Cancer Center

Amendment history

2026-09-10
Phase changed: Phase 2 → not applicable
Primary endpoint(s) modified1 entry, revised
Waslocal failure, pachymeningeal disease, classical leptomeningeal disease, symptomatic radiation necrosis, or death from any cause.
Nowlocal failure
The researchers are doing this study to see if treating people's brain tumors with stereotactic radiosurgery (SRS) before tumor resection surgery will prevent cancer cells from spreading to other areas of the brain, including the fluid and lining around the brain, during surgery, and lead to better surgical outcomes and fewer complications after surgery (post-surgery complications). Only one brain tumor (the index tumor) will be treated with the study radiosurgery and then removed by surgery. If there are other brain tumors, they will not be removed by surgery in this study, although they may be treated separately with standard radiation if the doctor decides it is needed.
Trial Details
NCT Number NCT07802353
Lead Sponsor Memorial Sloan Kettering Cancer Center
Conditions Brain Metastasases
Enrollment 50 participants
Start Date 2026-08-28
Primary Completion 2028-08 (estimated)
Study Completion 2028-08 (estimated)
Updated on ClinicalTrials.gov 2026-09-09