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To Evaluate If Preoperative 7 Days Low Calorie Diet Reduces Postoperative Morbidity in Liver Surgery

Name: To Evaluate If Preoperative 7 Days Low Calorie Diet Reduces Postoperative Morbidity in Liver Surgery — clinical trial record (NCT07801716)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: LowCaLi

StatusRecruiting

PhaseNot applicable

SponsorRegion Skane

Started2026-06-01

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Region Skane

146 trials monitored

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The rationale for this study is to evaluate whether a standardized, preoperative, short-term Low Calorie Diet (LCD) reduces intraoperative bleeding and postoperative morbidity in liver surgery. Participants with a BMI of 30 or higher, scheduled for liver surgery, if accepting participation, will be randomized to a 7 day LCD or no intervention. A previous small single center RCT have shown significantly reduced intraoperative blood loss and a tendency towards less postoperative complications. This multi-centre study aims to include enough patients with power to analyze also postoperative complications.

Trial Details

NCT Number	NCT07801716
Lead Sponsor	Region Skane
Conditions	Surgical Complications
Enrollment	200 participants
Start Date	2026-06-01
Primary Completion	2028-12-01 (estimated)
Study Completion	2029-07-01 (estimated)
Updated on ClinicalTrials.gov	2026-09-03