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TSBL-Based Versus BMI-Based Biliopancreatic Limb Length in One-Anastomosis Gastric Bypass

Study acronym: TSBL-OAGB
StatusRecruiting
PhaseNot applicable
Started2023-10-01
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This study compares two surgical techniques used during one-anastomosis gastric bypass (OAGB) surgery for patients with severe obesity. During this operation, surgeons create a bypass of part of the small intestine, and the length of this bypassed segment (called the biliopancreatic limb) affects both weight loss and the risk of nutritional side effects. In this trial, one group of patients has the limb length calculated individually based on the measured total length of their small intestine (TSBL-based method), while the other group receives a limb length based on standard body mass index (BMI) categories (BMI-based method). The study compares weight loss outcomes, improvement of obesity-related health problems, and complication rates between the two approaches over 12 months after surgery. The trial is being conducted at a single center in Almaty, Kazakhstan, and plans to enroll 100 patients total; this record reflects an interim analysis based on the first 75 patients enrolled.
Trial Details
NCT Number NCT07796503
Lead Sponsor National Scientific Center of Surgery named after A.N.Syzganov
Collaborators: Kazakh Medical University "Higher School of Public Health", Klaipėda University
Conditions Morbid Obesity, Obesity
Enrollment 100 participants
Start Date 2023-10-01
Primary Completion 2027-11-01 (estimated)
Study Completion 2027-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-09-01