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Physiology of Liberation

StatusNot Yet Recruiting
PhaseNot applicable
Started
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Record History

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  1. Notable Start date: Sep 2026 to Nov 2026
    • Interventions: Brief Standardized Mindfulness/Attention Instruction (Behavioral) to Brief Standardized Mindfulness/Attention Instruction (Behavioral)
    • Eligibility criteria expanded, about 9 words
    • Secondary endpoints: details revised at 3 of 3 entries
  2. Notable Enrollment increased: 20 → 36 participants
    • Trial arms changed: 2 → 3
    • Secondary endpoints: 2 to 3
    • Study description expanded, about 83 words
    v2
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This academic study examines how everyday experiences are related to short-term physiological reactivity and recovery and whether one or more brief standardized mindfulness/attention-instruction sessions change these patterns. Adults living in the United States who can read and understand the English study materials participate for up to 12 weeks and complete brief smartphone surveys several times a day during waking hours. Surveys include current experiences and recent alcohol and nicotine use; these reports are analyzed as contextual variables and are not automatic exclusion criteria. Some participants also use assigned non-invasive wearable sensors or blood-pressure monitors during prespecified measurement windows. Device output is used only for research measurement, not diagnosis, treatment, real-time medical decision-making, or patient management. In study waves with a randomized comparison, participants are randomized after consent to one or more brief mindfulness/attention-instruction sessions or time-matched no-instruction comparison sessions. Session duration, schedule, and allocation probabilities are specified before each study wave begins and applied consistently within that wave.
Trial Details
NCT Number NCT07780266
Lead Sponsor Boston University Charles River Campus
Conditions
(from sponsor)
Psychophysiological Reactivity and Recovery
Enrollment 36 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov