EUS-DFI in Solid Pancreatic Lesions

This prospective, international, multicenter observational study aims to evaluate the role of Endoscopic Ultrasound-guided Detective Flow Imaging (EUS-DFI) in the characterization of solid pancreatic lesions. The study will assess microvascularization patterns identified by EUS-DFI and their association with the final diagnosis, using histopathology or clinical follow-up as the reference standard. Secondary objectives include evaluating interobserver agreement and the diagnostic accuracy of DFI vascular patterns for differentiating benign and malignant pancreatic lesions.

NCT Number	NCT07763561
Lead Sponsor	Julio Iglesias García Collaborators: Ospedale San Raffaele, Università Vita Salute San Raffaele, Policlinico Universitario Campus Bio-Medico, Leids Universitair Medisch Centrum (LUMC), Leiden
Conditions	Pancreatic Neoplasms, Pancreatic Solid Lesions
Enrollment	48 participants
Start Date	2026-12-01
Primary Completion	2027-06-01 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-13