Fatigue in Long-Haul Operations

The purpose of the present study is to test novel countermeasures to reduce fatigue among airline pilots during long-haul flight operations. The investigators will collect objective and subjective sleep, sleepiness, workload, and performance data from active-duty line pilots flying long-haul flight operations (\>8 hours). Data will be collected during days off prior to the trip start, during flights and layover, and during days off following the trip end.

NCT Number	NCT07761611
Lead Sponsor	National Aeronautics and Space Administration (NASA) Collaborators: Civil Aerospace Medical Institute, Washington State University
Conditions	Alertness, Fatigue, Mood, and Performance, Calorie Restriction and Light Intervention
Enrollment	118 participants
Start Date	2026-09
Primary Completion	2029-07 (estimated)
Study Completion	2029-07 (estimated)
Updated on ClinicalTrials.gov	2026-08-12