Clinical Trial

A Real-World Study of Treatment Patterns, Tolerability and Effectiveness of CDK4/6 Inhibition in HR+, HER2-negative Metastatic Breast Cancer Patients

Completed
View on ClinicalTrials.gov →
Summary
The aim of this study was to assess real-world treatment patterns and tolerability of ribociclib among patient populations historically underrepresented in clinical trials - specifically older adults and Black/African American patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer (mBC). The study was conducted using data from a nationwide database derived from electronic health record (EHR) data collected from oncology practices across the United States. The study population was drawn from community and academic oncology practices within the health research network.
Trial Details
NCT Number NCT07760714
Lead Sponsor Novartis Pharmaceuticals
Conditions Breast Cancer
Enrollment 945 participants
Start Date 2025-02-26
Primary Completion 2025-08-29 (estimated)
Study Completion 2025-08-29 (estimated)
Updated on ClinicalTrials.gov 2026-08-14