Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07756658 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 31 days later Dec 17, 2026 → Jan 17, 2027
See other at-risk trials from Applied Science & Performance Institute

Record History

See every version on ClinicalTrials.gov ↗

  1. Recruitment opened Show 8 more changesShow less
    • Lead sponsor: Applied Science & Performance Institute to Applied Science & Performance Institute
    • Primary endpoints: details revised at 1 of 4 entries
    • Primary and study completion pushed from Dec 17, 2026 to Jan 17, 2027
    • Start date changed from estimate of Aug 17, 2026 to Sep 4, 2026
    • Eligibility criteria shortened, about 9 words
    • Secondary endpoints: details revised at 6 of 6 entries
    • Study description revised
    • Site details revised
  2. Secondary endpoints: details revised at 1 of 6 entries
    • Study description expanded, about 2 words
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will be a randomized, double-blind, placebo-controlled trial. It will be conducted over a 8-week intervention investigating the effects of creatine (5g Creatine monohydrate); placebo control (5g resistant dextrin), and a combination group containing both creatine and tyrosol (5g creatine monohydrate + 150mg tyrosol/day). Endurance, strength, cognition, and fatigue resistance will be examined through repeated strength and endurance testing (described below). Participants who pass initial screening will be invited on-site for day one (Visit 1) of testing where the participants will proceed with a series of tests which will include the following: (1) body composition; (2) mood and cognitive testing; (3) full-body strength testing; (4) 5RM (repetition maximum) bench press, leading to multiple sets of bench press (based on the previous weight) completed to failure; (5) finally, a time to exhaustion endurance test will be conducted followed by (6) repeat cognitive testing. After the 8-week supplementation period (\~56-60 days), all original measures will be repeated as before in the same order (Visit 2). Approximately 24 hours later (Visit 3) participants will complete a questionnaire for muscle soreness remotely, and again at 48 hours post-Visit 2 (visit 4).
Trial Details
NCT Number NCT07756658
Lead Sponsor Applied Science & Performance Institute
Conditions
(from sponsor)		 Tyrosol, Creatine, Endurance Performance, Cognition, Mood
Related terms Myalgia
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov