Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms

This prospective real-world cohort study aims to compare early postoperative complications between flow diverter treatment and stent-assisted coiling in patients with unruptured wide-neck intracranial bifurcation aneurysms. A total of 274 patients from three centers in China will be enrolled and assigned to the flow diverter group or the stent-assisted coiling group according to the treatment received in routine clinical practice. The primary outcome is a composite of any stroke or all-cause death within 30 days after the procedure. The study will also collect demographic, clinical, laboratory, imaging, aneurysm morphological, procedural, and follow-up data to evaluate the safety of these two endovascular treatment strategies in a real-world setting.

NCT Number	NCT07754188
Lead Sponsor	Nanfang Hospital, Southern Medical University Collaborators: Zhujiang Hospital, Guangdong Province People's Hospital
Conditions	Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm, Wide-Neck Aneurysm
Enrollment	274 participants
Start Date	2026-03-19
Primary Completion	2027-03-19 (estimated)
Study Completion	2028-03-19 (estimated)
Updated on ClinicalTrials.gov	2026-08-10