Clinical Trial

Local Anesthetic Infiltration for Pain Control After Orthopedic Wide Excision

Not Yet Recruiting
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Summary
This study evaluates whether injecting a local anesthetic mixture (ropivacaine, morphine, ketorolac, and epinephrine) under the skin at the incision site before wound closure reduces pain after orthopedic wide excision surgery for bone or soft tissue tumors. Participants will be randomly assigned to receive either the local anesthetic mixture or a saline control injection. Neither participants nor the study team assessing outcomes will know which treatment was given. The main goal is to determine whether this injection reduces the amount of opioid pain medication needed during the first 24 hours after surgery. The study will also assess pain scores, nausea and vomiting, and quality of recovery.
Trial Details
NCT Number NCT07753629
Lead Sponsor Seoul National University Hospital
Conditions Wide Excision, Postoperative Pain
Enrollment 58 participants
Start Date 2026-08-07
Primary Completion 2027-07-31 (estimated)
Study Completion 2028-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-07