Clinical Trial

Effects of Long-Term Antihistamine Use on Mandibular Bone in Children

Not Yet Recruiting
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Summary
The purpose of this retrospective radiographic study is to evaluate the effects of long-term H1 antihistamine use on mandibular trabecular bone structure in children aged 8-10 years. Mandibular trabecular bone will be assessed using fractal dimension analysis and the panoramic mandibular index on digital panoramic radiographs. Three groups will be compared: children receiving long-term H1 antihistamine therapy, allergic children without antihistamine use, and age- and sex-matched healthy controls. The findings will provide information on whether long-term antihistamine therapy is associated with alterations in mandibular bone microarchitecture.
Trial Details
NCT Number NCT07752485
Lead Sponsor Recep Tayyip Erdogan University Training and Research Hospital
Conditions Fractals, Panoramic Radiography
Enrollment 84 participants
Start Date 2026-08-03
Primary Completion 2026-08-30 (estimated)
Study Completion 2026-09-03 (estimated)
Updated on ClinicalTrials.gov 2026-08-07