ProNephro NGAL Test for Early Detection of Acute Kidney Injury in Adult ICU Patients (ALPACA)

The purpose of this study is to evaluate the performance of the ProNephro AKI™ (NGAL) test for identifying critically ill adults at risk of developing moderate to severe acute kidney injury (KDIGO Stage 2/3) within 48 to 72 hours of ICU admission. The study will assess how accurately the test predicts acute kidney injury by evaluating its sensitivity, specificity, positive predictive value, and negative predictive value. Participants will provide blood and urine samples for testing.

NCT Number	NCT07751913
Lead Sponsor	BioPorto Diagnostics
Conditions	Acute Kidney Injury
Enrollment	800 participants
Start Date	2026-08
Primary Completion	2027-11 (estimated)
Study Completion	2028-05 (estimated)
Updated on ClinicalTrials.gov	2026-08-10