Clinical Trial

Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL

Not Yet Recruiting
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Summary
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones. Participants with renal stones measuring 2-3 cm will be randomly assigned to either tubeless percutaneous nephrolithotomy with nebulized Glubran 2 used to seal the access tract or conventional percutaneous nephrolithotomy with placement of a nephrostomy tube. The study will evaluate whether the Glubran 2-assisted tubeless technique is safe and effective and whether it can reduce postoperative pain, bleeding, hospital stay, urine leakage, and other complications while maintaining a satisfactory stone-free rate.
Trial Details
NCT Number NCT07749807
Lead Sponsor Benha University
Conditions Kidney Calculi, Nephrolithiasis
Enrollment 100 participants
Start Date 2026-09-01
Primary Completion 2027-02-01 (estimated)
Study Completion 2027-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-06