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Pneumococcal Carriage Duration

Name: Pneumococcal Carriage Duration — clinical trial record (NCT07748832)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhaseNot specified

SponsorUniversity of Central Florida

Started2026-07-21

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University of Central Florida

48 trials monitored

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Streptococcus pneumoniae (SPN) remains a leading cause of respiratory disease in young children despite widespread vaccination. Understanding the duration of pneumococcal carriage, patterns of co-colonization, and the influence of viral infections and the respiratory microbiome is essential to evaluate next-generation pneumococcal vaccines and inform public health strategies. Current data on Streptococcus pneumoniae carriage dynamics are limited in U.S. pediatric populations. This study aims to generate updated estimates of Streptococcus pneumoniae colonization and explore microbial interactions using high-resolution longitudinal sampling and genomic methods.

Trial Details

NCT Number	NCT07748832
Lead Sponsor	University of Central Florida Collaborators: Merck Sharp & Dohme LLC
Conditions	Pneumococcal Carriage
Enrollment	60 participants
Start Date	2026-07-21
Primary Completion	2027-07 (estimated)
Study Completion	2027-07 (estimated)
Updated on ClinicalTrials.gov	2026-08-06