Clinical Trial

SAL0137 Phase I Study in in Healthy Participants With or Without Elevated Lp(a)

Active, Not Recruiting Phase 1
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Summary
This study is divided into 3 parts: Part A, Part B, and Part C. Part A is a randomized, double-blind, placebo-controlled, single ascending dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of SAL0137 tablets; Part B is a randomized, double-blind, placebo-controlled, multiple ascending dose study with once-daily administration for 14 consecutive days to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple QD oral doses of SAL0137 tablets.
Trial Details
NCT Number NCT07745114
Lead Sponsor Shenzhen Salubris Pharmaceuticals Co., Ltd.
Conditions Healthy Participants, Elevated Lp(a)
Enrollment 144 participants
Start Date 2026-01-04
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-08-04