Clinical Trial

Knee Ligament Stiffness Across Ethnicities Before and After Osteoarthritis Treatment

Recruiting
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Summary
This prospective clinical study aims to establish normative values of knee ligament stiffness across different ethnic populations using shear wave elastography (SWE) and to investigate biomechanical alterations associated with knee osteoarthritis (OA). Healthy adults and patients with symptomatic knee OA will undergo standardized SWE examinations of the anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), medial collateral ligament (MCL), and lateral collateral ligament (LCL), together with clinical assessments. For patients who subsequently receive clinically indicated ultrasound-guided injection therapy, follow-up SWE and clinical evaluations will be performed to investigate changes in ligament stiffness after treatment.
Trial Details
NCT Number NCT07744789
Lead Sponsor National Taiwan University Hospital
Collaborators: National Taiwan University Hospital Beihu Branch
Conditions Knee Osteoarthritis
Enrollment 208 participants
Start Date 2023-07-26
Primary Completion 2027-07-01 (estimated)
Study Completion 2027-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-06