Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders

This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and obsessive-compulsive disorder, based on family history or subthreshold emotional or behavioral symptoms. Participants will be followed for two years. Clinical assessments, questionnaires, EEG, biological samples, and MRI will be collected at scheduled intervals. The study aims to identify factors associated with the onset and progression of these disorders and support early risk identification.

NCT Number	NCT07744490
Lead Sponsor	Shanghai Mental Health Center Collaborators: Fudan University, Southeast University, China
Conditions	High Risk, Depression / Major Depressive Disorder, Anxiety Disease, Obsessive - Compulsive Disorder
Enrollment	200 participants
Start Date	2026-07-25
Primary Completion	2030-12-31 (estimated)
Study Completion	2030-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-04