Clinical Trial

Gestational Response, Outcomes, and Weight After GLP-1 Use

Study acronym: GROW
Recruiting
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Summary
The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes. The main aims of the study are to: * Compare gestational weight gain between women with preconception GLP-1RA exposure and those without exposure. * Compare obstetrical outcomes between women with preconception GLP-1RA exposure and those without exposure. Researchers will compare pregnant women with a history of GLP-1RA use to pregnant women who have not used a GLP-1RA to compare differences. Participants will be asked to complete questionnaires at multiple timepoints during and after pregnancy that ask questions about medication history, thoughts and feelings around food, etc.
Trial Details
NCT Number NCT07743567
Lead Sponsor University of Kansas Medical Center
Conditions Pregnant Individuals, Obesity & Overweight, Gestational Weight Gain
Enrollment 400 participants
Start Date 2026-04-13
Primary Completion 2028-04 (estimated)
Study Completion 2028-04 (estimated)
Updated on ClinicalTrials.gov 2026-08-04