Empowering Veterans in Research Effectively Using Virtual Engagement Tools

Cardiovascular disease is the leading cause of death among Veterans. Clinical trials are essential for developing better treatments, but Veterans remain underrepresented in these studies due to barriers including limited health literacy, lack of awareness, and mistrust. Current outreach approaches rely on either in-person physician conversations, which are limited by workforce constraints, or mailed letter invitations, which often fail to engage Veterans with limited health literacy. This study tests whether AI-generated video avatars can improve Veteran engagement in cardiovascular clinical trials.

NCT Number	NCT07741955
Lead Sponsor	Stanford University Collaborators: Palo Alto Veterans Institute for Research, VA Palo Alto Health Care System
Conditions	Atrial Fibrillation (AF), Cardiovascular Diseases
Enrollment	100,000 participants
Start Date	2026-07
Primary Completion	2030-07 (estimated)
Study Completion	2030-07 (estimated)
Updated on ClinicalTrials.gov	2026-08-03