Clinical Trial

Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity

Study acronym: ATHENA
Not Yet Recruiting
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Summary
The goal of this clinical trial is to determine whether the extra-virgin olive oil (EVOO) phenolic dietary supplement can improve memory function and modulate biomarkers among individuals with mild cognitive impairment (MCI). The main questions it aims to answer are: * Does dietary supplementation with EVOO phenolics improve cognitive function? * What would be the effect of the EVOO dietary supplement on other MCI-related biomarkers, including vascular function and biological pathways? Researchers will compare the EVOO dietary supplements with a placebo (a look-alike substance that contains no EVOO phenolics) Participants will: * Take EVOO dietary supplements or a placebo daily for 6 months * Visit the study site during the 6-month study for screening and testing.
Trial Details
NCT Number NCT07741773
Lead Sponsor Augusta University
Conditions Mild Cognitive Impairment (MCI)
Enrollment 20 participants
Start Date 2026-09-01
Primary Completion 2028-08-31 (estimated)
Study Completion 2028-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-03