Impact of Perioperative Antibiotic Use on Surgical Scarring

This retrospective observational cohort study will evaluate whether perioperative antibiotic use is associated with long-term surgical scar outcomes. The study will include adult patients who underwent body surface surgery at Nanfang Hospital between January 1, 2005 and January 1, 2025 and have available surgical, medication, and scar-related clinical records. The study will not assign participants to any treatment. Researchers will review existing medical records, perioperative antibiotic exposure, surgical characteristics, complications, and scar assessments or photographs. Scar outcomes will be assessed using modified visual analogue scale scores, scar width, scar type, and scar-related complications.

NCT Number	NCT07741591
Lead Sponsor	Nanfang Hospital, Southern Medical University
Conditions	Surgical Scar, Postoperative Scar
Enrollment	5,000 participants
Start Date	2026-08-03
Primary Completion	2026-08-15 (estimated)
Study Completion	2026-08-15 (estimated)
Updated on ClinicalTrials.gov	2026-08-03