Clinical Trial

Povidone Iodine for Caries Prevention

Not Yet Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1. How will home use of Povidone Iodine, as an adjunct treatment to standard dental care, reduce the incidence of tooth decay? 2. How will home use of Povidone Iodine reduce the mouth germs responsible for tooth decay? 3. If Povidone Iodine use is accompanied by probiotic use, will its effectiveness be even better than Povidone Iodine alone? Participants will: 1. Provide a plaque sample at the beginning of the study. 2. Swab their children's teeth once a week for one month and then monthly thereafter. Some participants may be asked to use probiotic drops nightly after brushing their teeth. 3. Keep a record of compliance. 4. Return every 6 months for a dental exam and to provide a plaque sample. Keep a diary of their symptoms and the number of times they use a rescue inhaler
Trial Details
NCT Number NCT07741409
Lead Sponsor Jeffrey A. Banas
Conditions Dental Caries
Enrollment 174 participants
Start Date 2026-08-03
Primary Completion 2027-12-31 (estimated)
Study Completion 2028-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-08-03