Clinical Trial

Cognitive Processing of Natural Sequences in Humans and Artificial Intelligence (AI)

Study acronym: SEQUOIA
Not Yet Recruiting
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Summary
The goal of this study is to identify electrical patterns in the cortex that enable the generation of predictions in natural auditory sequences such as speech and music. Between 500 and 700 participants in total (250 to 350 normally hearing participants (including 60 to 120 participants from West Africa and 60 to 120 participants from Western Europe) and 250 to 350 participants with hearing loss (no restrictions on origin)). Participants will listen to naturally recorded music and speech via headphones. They will be asked to rate these stimuli on a scale from 0 to 10 in terms of pleasure and comprehension, using a keyboard and mouse or voice input. Additionally, they will be required to sing or produce novel/improvised vocal responses using high-fidelity microphones. This entire procedure will be conducted under electroencephalography (EEG) to record neuronal responses throughout the process.
Trial Details
NCT Number NCT07740070
Lead Sponsor Institut Pasteur
Collaborators: IHU reConnect
Conditions Hearing Disorders and Deafness
Enrollment 700 participants
Start Date 2026-09
Primary Completion 2030-11 (estimated)
Study Completion 2033-11 (estimated)
Updated on ClinicalTrials.gov 2026-07-31