Periodontitis on Gingival Crevicular Fluid Metobolomics

This cross-sectional observational study will compare the gingival crevicular fluid metabolomic profile of 30 adults with periodontitis and 30 periodontally healthy adults. Participants will undergo a periodontal examination and gingival crevicular fluid collection during a single study visit. Targeted metabolomic analysis will be used to identify differences between the two groups and associations with periodontal clinical parameters.

NCT Number	NCT07739732
Lead Sponsor	University of Catania
Conditions	Periodontitis
Enrollment	60 participants
Start Date	2026-05-04
Primary Completion	2026-11-16 (estimated)
Study Completion	2026-12-18 (estimated)
Updated on ClinicalTrials.gov	2026-07-31