Clinical Trial

Acute Effects of Estradiol Administration on Brain Function During Fear Learning

Study acronym: EstroFearGen
Not Yet Recruiting Early Phase 1
View on ClinicalTrials.gov →
Summary
The goal of current study is to better understand how fear is processed in the brain and how these processes are influenced by cognition and hormones. This research will focus specifically on postmenopausal female adults, because age-related changes in cognition and declining estrogen levels may contribute to anxiety symptoms and PTSD risk later in life.
Trial Details
NCT Number NCT07737613
Lead Sponsor University of Arizona
Conditions PTSD and Trauma-related Symptoms, Cognitive Decline in Older Adults, Post Menopausal Women
Enrollment 30 participants
Start Date 2026-08
Primary Completion 2027-08 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-30