Screening With Portable X-rays for Rapid Recognition of TB

SPOT-TB (Screening with Portable X-rays for rapid recOgniTion of TB) is a prospective study evaluating a community-based tuberculosis (TB) screening strategy for migrant populations in New York City. The screening intervention integrates mobile ultra-portable digital chest radiography with artificial intelligence-assisted image interpretation, tuberculosis symptom assessment, latent tuberculosis infection testing, and HIV testing. Participants with concerning screening findings are referred for appropriate clinical evaluation. The study will evaluate the feasibility, acceptability, and effectiveness of this integrated screening strategy for improving early identification of active pulmonary tuberculosis and linkage to care in community settings.

NCT Number	NCT07737275
Lead Sponsor	Columbia University Collaborators: National Institute of Allergy and Infectious Diseases (NIAID)
Conditions	Tuberculosis (TB), Tuberculosis Infection, Latent, HIV (Human Immunodeficiency Virus)
Enrollment	1,000 participants
Start Date	2026-08-15
Primary Completion	2027-05-14 (estimated)
Study Completion	2028-03-10 (estimated)
Updated on ClinicalTrials.gov	2026-07-30