Venlafaxine for Non-specific Low Back Pain

Chronic non-specific low back pain is the leading cause of productivity loss and disability worldwide, constituting a major public health challenge. This study aims to systematically evaluate and compare the role of the antidepressant drug Venlafaxine in chronic non-specific low back pain, which is of critical importance for optimising clinical practice and developing precise, individualised treatment regimens.

NCT Number	NCT07737158
Lead Sponsor	Beijing Tiantan Hospital
Conditions	Non-specific Low Back Pain, Pain Management
Enrollment	228 participants
Start Date	2026-09-01
Primary Completion	2028-12-30 (estimated)
Study Completion	2028-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-30