Clinical Trial

Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants

Study acronym: VITAL
Not Yet Recruiting
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Summary
Preterm infants are at increased risk of vitamin A deficiency because they are born with low vitamin A stores and depend largely on breast milk to meet their nutritional needs. This study will evaluate whether daily maternal vitamin A supplementation increases vitamin A concentrations in the breast milk of mothers who deliver infants before 29 weeks of gestation. Participants will receive a commercially available oral multivitamin supplement containing 1,300 mcg retinol activity equivalents (RAE) of vitamin A daily for four months after delivery. Breast milk samples will be collected at 2 weeks, 2 months, and 4 months postpartum to measure vitamin A concentrations. The study will assess whether maternal supplementation is a feasible approach for increasing breast milk vitamin A concentrations in mothers of preterm infants.
Trial Details
NCT Number NCT07736768
Lead Sponsor University of Mississippi Medical Center
Conditions Premature, Preterm Infant Health, Vitamin A Deficiency, Human Milk, Breastfeeding
Enrollment 20 participants
Start Date 2026-08-01
Primary Completion 2027-07-30 (estimated)
Study Completion 2027-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-30