The research was conducted between January 2025 and May 2025 using a randomized controlled experimental design with a pre-test-post-test pproach. A total of 76 nurses working at a state university hospital in Istanbul participated in the study. The experimental group received training through the Pecha-Kucha method, while the control group received traditional instruction. Data were collected using the Individual Characteristics Form, the Nurses' Knowledge Assessment Form for Anticoagulant Drug Administration, the Skill Assessment Form for Anticoagulant Drug Administration, and the Visual Analog Scale.