Efficacy and Safety of HRS-9190 in General Anesthesia

A multicenter, randomized, double - blind, placebo - controlled, parallel - group phase III clinical trial was carried out to evaluate the efficacy and safety of HRS - 9190 for skeletal muscle relaxation during tracheal intubation in the induction and maintenance phases of general anesthesia. The primary objective was to evaluate the effectiveness of HRS - 9190 in achieving skeletal muscle relaxation during tracheal intubation in the induction and maintenance phases of general anesthesia. The secondary objective was to assess the safety and pharmacokinetic profile of HRS - 9190.

NCT Number	NCT07733245
Lead Sponsor	The Third Xiangya Hospital of Central South University Collaborators: Jiangsu Hengrui Pharmaceutical Co., Ltd.
Conditions	Adult Participants Requiring Tracheal Intubation Under General Anesthesia for Elective Surgery
Enrollment	320 participants
Start Date	2026-07-28
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-29