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PROSPECT Registry for Individuals at Risk for Genetic Prion Disease

Study acronym: PROSPECT
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Eligibility criteria expanded, about 8 words
    • Publications: details revised at 1 of 1 entry
  2. Sponsor changed: University Hospitals Cleveland Medical Center to Brian Applebyv3 Show 4 more changesShow less
    • Recruitment opened
    • Enrollment increased: 1000 → 2000 participants
    • Study sites: 0 to 1
    • Start date changed from estimate of Aug 17, 2026 to Aug 25, 2026
  3. Re-verified, no change to tracked fieldsv2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
PROSPECT is a prospective observational registry and longitudinal natural history study of adults at risk for genetic prion disease.
Trial Details
NCT Number NCT07732608
Lead Sponsor Brian Appleby
Collaborators: Case Western Reserve University, CJD Foundation, Prion Alliance
Conditions
(from sponsor)		 Prion Diseases
Related terms Prion Diseases
Enrollment 2,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov