TRYPTYR as a Treatment for Patients With Dry Eye Disease (DED)

The purpose of this research study is to determine the effectiveness of TRYPTYR as a treatment for Dry Eye Disease. The primary efficacy variable is change from baseline in the Ocular Surface Disease Index (OSDI) at week 2. The co-primary efficacy variables are change from baseline in the National Eye Institute (NEI) scale of the cornea and NEI scale of the conjunctiva at 1 month (the third visit).

NCT Number	NCT07732010
Lead Sponsor	NYU Langone Health
Conditions	Dry Eye Disease (DED)
Enrollment	50 participants
Start Date	2026-07-06
Primary Completion	2027-04-20 (estimated)
Study Completion	2027-05-25 (estimated)
Updated on ClinicalTrials.gov	2026-07-28