Clinical Trial

Transcranial Magnetic Stimulation for Freezing of Gait in Parkinson's Disease

Study acronym: PD-FOG-TMS
Completed
View on ClinicalTrials.gov →
Summary
This study evaluated transcranial magnetic stimulation (TMS) for freezing of gait in patients with Parkinson's disease. Participants with Parkinson's disease and freezing of gait received conventional TMS protocols, and their clinical, gait, and neurophysiological outcomes were assessed. Patients who did not achieve sufficient improvement after conventional TMS were further treated with a combined primary motor cortex and cerebellar stimulation protocol. The study aimed to identify factors associated with differential response to conventional TMS and to explore whether cerebellar stimulation could improve symptoms in treatment-resistant patients.
Trial Details
NCT Number NCT07731841
Lead Sponsor The First Affiliated Hospital with Nanjing Medical University
Conditions Parkinson Disease (PD)
Enrollment 85 participants
Start Date 2021-09-01
Primary Completion 2025-12-30 (estimated)
Study Completion 2026-06-23 (estimated)
Updated on ClinicalTrials.gov 2026-07-28