Clinical Trial

IV DEXAMETHASONE VS. METHYLPREDNISOLONE IN CHILDREN WITH SEVERE ASTHMA EXACERBATION

Study acronym: IV:INTRAVENOUS
Completed Phase 4
View on ClinicalTrials.gov →
Summary
The study aims to determine whether a two-day intravenous course of dexamethasone is non-inferior to a conventional five-day intravenous course of methylprednisolone in children presenting with severe asthma exacerbations. To answer this question, researchers randomly assign eligible children to receive either IV dexamethasone or IV methylprednisolone. The clinical response to the treatments is objectively evaluated and compared using the Pediatric Respiratory Assessment Measure (PRAM) score at the 4th hour of treatment and on the 2nd day following hospital discharge.
Trial Details
NCT Number NCT07731217
Lead Sponsor Istanbul Medeniyet University
Conditions Status Asthmaticus, Asthma (Diagnosis), Asthma Exacerbations
Enrollment 129 participants
Start Date 2025-09-01
Primary Completion 2026-07-01 (estimated)
Study Completion 2026-07-15 (estimated)
Updated on ClinicalTrials.gov 2026-07-28