Clinical Trial

Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity

Study acronym: TAUMUSCLE
Active, Not Recruiting
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Summary
This randomized clinical trial aims to investigate the effects of multicomponent concurrent exercise training associated or not with taurine supplementation on intramuscular fat infiltration, physical performance, transcriptomic profile, and metabolomic profile in older women with obesity. Forty women aged 60 to 75 years with obesity will be randomized into four groups: control, exercise, taurine, and exercise plus taurine. The intervention will last 16 weeks. Outcomes include magnetic resonance imaging, body composition, muscle biopsy, blood biomarkers, functional capacity tests, transcriptomic analysis, and metabolomic analysis.
Trial Details
NCT Number NCT07730255
Lead Sponsor University of Sao Paulo
Conditions Obesity (BMI>30)
Enrollment 44 participants
Start Date 2026-05-01
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-28