Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

This study will evaluate the safety and effectiveness of a single injection of EO2002 at one of two dose levels (150,000 or 500,000 magnetic human corneal endothelial cells \[mHCECs\]), compared with a placebo injection, in participants with corneal edema caused by corneal endothelial dysfunction.

NCT Number	NCT07729137
Lead Sponsor	Emmecell
Conditions	Corneal Edema, Fuchs, Fuchs Dystrophy, Fuchs' Endothelial Dystrophy, Endothelial Corneal Dystrophy, Corneal Endothelial Decompensation, Corneal Endothelial Cell Loss, Corneal Endothelial Disorder +4 more
Enrollment	121 participants
Start Date	2026-09
Primary Completion	2027-08 (estimated)
Study Completion	2028-02 (estimated)
Updated on ClinicalTrials.gov	2026-07-29