Clinical Trial

Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar Region

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Summary
This randomized clinical trial will evaluate the effect of using an enamel matrix derivative during immediate dental implant placement in the mandibular molar region. Patients who require extraction of a non-restorable mandibular molar and immediate implant placement will be randomly assigned to receive an implant placed with enamel matrix derivative or without enamel matrix derivative. Clinical and radiographic outcomes, including implant stability and peri-implant bone changes, will be assessed over a follow-up period of six months. The results of this study aim to determine whether the use of enamel matrix derivative improves osseointegration and healing around immediate dental implants.
Trial Details
NCT Number NCT07727655
Lead Sponsor Mansoura University
Conditions Tooth Loss
Enrollment 24 participants
Start Date 2026-06
Primary Completion 2026-09 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-07-27