VNS Algorithm for Advanced Dosing

The goal of this clinical trial is to compare the standard programming of the VNS device (Control) to a modified programming (Augusta Way) in adults with epilepsy. The main question it aims to answer is: Does the modified programming of the VNS reduce seizures faster than the standard programming? Participants in both groups will: 1. Attend up to 3 study visits every 3 months for 2 years 2. Answer questionnaires to assess quality of life and cognitive function 3. Maintain a diary of seizure activity

NCT Number	NCT07725601
Lead Sponsor	Fernando Vale Collaborators: Augusta University
Conditions	Epilepsies
Enrollment	80 participants
Start Date	2025-08-01
Primary Completion	2028-12-31 (estimated)
Study Completion	2030-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-24