Structural and Clinical Predictors of Cognitive Impairment After Surgical Treatment for Ruptured Cerebral Aneurysms

This study investigates the clinical and structural predictors of long-term cognitive impairment in patients who underwent microsurgical clipping for aneurysmal subarachnoid hemorrhage. Using a retrospective cohort with prospective neuropsychological and MRI assessments, it aims to identify factors associated with late cognitive deficits and improve prognostic stratification, rehabilitation planning, and long-term patient care.

NCT Number	NCT07723131
Lead Sponsor	University of Campinas, Brazil Collaborators: Hospital de Clinicas da Unicamp - SP
Conditions	Subarachnoid Aneurysm Hemorrhage, Microsurgery, Cognitive Impairment
Enrollment	150 participants
Start Date	2026-08
Primary Completion	2029-07 (estimated)
Study Completion	2029-12 (estimated)
Updated on ClinicalTrials.gov	2026-07-23