Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)

Study acronym: VACC-UP
StatusRecruiting
PhaseNot applicable
Started

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Record History

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  1. Recruitment opened Show 5 more changesShow less
    • Start date changed from estimate of Sep 2026 to Sep 30, 2026
    • Eligibility criteria expanded, about 7 words
    • Secondary endpoints: details revised at 2 of 3 entries
    • Site details revised at 2 of 2 sites
    • Publications: details revised at 3 of 3 entries
  2. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
The aim of this study is to evaluate the effect of offering intrahospital influenza vaccination as an adjunct to active counseling during the index hospitalization to adult patients hospitalized for acute coronary syndrome (ACS) or congestive heart failure (CHF), compared with active counseling alone, on influenza vaccination rates in patients at high cardiovascular risk. Patients are randomized 1:1 to either an offer of bedside intrahospital influenza vaccination according to the recommendations of the German Standing Vaccination Committee (STIKO) in addition to standardized active counseling (intervention group), or standardized active counseling plus the standard-of-care recommendation for ambulatory vaccination in the discharge papers (control group). The primary endpoint is the influenza vaccination rate at the end of the index season (March 31).
Trial Details
NCT Number NCT07721649
Lead Sponsor Stephan Baldus
Collaborators: Sanofi
Conditions
(from sponsor)		 Acute Coronary Syndrome, Heart Failure, Influenza, Human, Cardiovascular Diseases, Vaccination Refusal
Related terms Acute Coronary Syndrome, Cardiovascular Diseases, Heart Failure, Influenza, Human, Vaccination Hesitancy, Vaccination Refusal
Enrollment 482 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov