Clinical Trial

Nociception Level Index Monitoring During Cesarean Section

Study acronym: NOL-CS
Completed
View on ClinicalTrials.gov →
Summary
This prospective randomized controlled trial evaluated the effect of nociception level (NOL) index-guided intraoperative analgesia on postoperative pain management in patients undergoing elective cesarean section under general anesthesia. Sixty patients were randomly assigned to either NOL-guided analgesia or standard intraoperative monitoring. The primary outcome was postoperative pain intensity assessed using the visual analog scale (VAS) during the first 24 hours after surgery. Secondary outcomes included postoperative opioid requirements and time to first breastfeeding. The study aimed to determine whether objective intraoperative nociception monitoring could improve postoperative analgesia and enhance early maternal recovery.
Trial Details
NCT Number NCT07720440
Lead Sponsor Istinye University
Conditions Cesarean Section, Postoperative Pain After Cesarean Section, Pain Management
Enrollment 60 participants
Start Date 2023-08-15
Primary Completion 2024-02-15 (estimated)
Study Completion 2024-02-15 (estimated)
Updated on ClinicalTrials.gov 2026-07-22