CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans

This trial evaluates CITE, a retrieve-and-verify layer that audits an AI-generated care plan against a full-text evidence corpus and flags patient-specific codifiable safety hazards to the clinician. The co-primary outcomes are how accurately CITE flags these hazards (sensitivity and specificity versus blinded clinician adjudication) and its clinician alert burden and acceptance, compared with AI care plans using safety guardrails alone and with unassisted clinician care, in Medicaid primary care.

NCT Number	NCT07718893
Lead Sponsor	Waymark Collaborators: University of California, San Francisco
Conditions	Quality of Health Care, Patient Safety, Clinical Decision Support
Enrollment	240 participants
Start Date	2026-09
Primary Completion	2027-06 (estimated)
Study Completion	2027-09 (estimated)
Updated on ClinicalTrials.gov	2026-07-22