Clinical Trial

Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia.

Recruiting
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Record status
This record was last updated July 22, 2026 (before its estimated July 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized controlled trial compares laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in patients undergoing surgical treatment for hiatal hernia associated with gastroesophageal reflux disease. Participants will be randomly assigned to one of two surgical groups. The study will evaluate postoperative pain, health-related quality of life, hospital stay, recurrence of reflux symptoms, gas-bloat symptoms, operative time, fundoplication time, and postoperative complications.
Trial Details
NCT Number NCT07718828
Lead Sponsor Sofia Med Hospital
Conditions Hiatal Hernia, Paraesophageal, Hiatal Hernia Large, Hiatal Hernia With Gastroesophageal Reflux Disease
Enrollment 200 participants
Start Date 2023-05-29
Primary Completion 2026-07-30 (estimated)
Study Completion 2027-01-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-22