The Turbine-based CO2 Insufflator Pediatric Feasibility Study

A novel CO2 insufflator, the turbine-based insufflator, has been developed to improve minimal invasive surgery. Turbine technology permits accurate pressure control resulting in an intra-abdominal volume that is dynamically adapted to ventilation. In addition, oscillometric measurements are performed to measure the abdominal compliance of the patient. This feasibility trial primarly aims to evaluate the technologic feasibility during pediatric laparoscopic surgery. Secondary outcomes are pressure stability, comparison of intra-abdominal pressure stability between the standard CO2 insufflator and turbine-based insufflator, and comparison of ventiliation pressures between these insufflators.

NCT Number	NCT07715968
Lead Sponsor	Erasmus Medical Center Collaborators: Politecnico di Milano University, Health∼Holland, Topsector Life Sciences & Health, Spatium Medical B.V.
Conditions	Laparoscopy, Pneumoperitoneum
Enrollment	12 participants
Start Date	2026-02-10
Primary Completion	2026-12-01 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-21