Clinical Trial

Vestibular Perception Gates Autonomic Responses to Sinusoidal Galvanic Vestibular Stimulation

Study acronym: GVS-HRV
Completed
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Summary
Brief Summary This randomized, double-blind, sham-controlled clinical trial is designed to investigate whether repeated sinusoidal galvanic vestibular stimulation (GVS) influences cardiac autonomic regulation in healthy adults during their routine occupational activities, and to determine whether these effects depend on subjective vestibular perception (dizziness) experienced during stimulation. The main questions it aims to answer are: Does repeated sinusoidal GVS alter heart rate variability (HRV) in healthy adults during their normal work activities? Do autonomic responses to GVS depend on the subjective intensity of dizziness experienced during stimulation? Does repeated GVS affect psycho-emotional well-being, including depressive and anxiety symptoms? Researchers will compare active GVS to sham stimulation to see if active stimulation produces measurable changes in cardiac autonomic regulation and whether these changes differ between participants reporting stronger versus minimal dizziness. Participants will undergo baseline assessment, complete four consecutive daily sessions of active or sham GVS, and undergo post-intervention assessment. Autonomic responses will be assessed using multiple HRV indices.
Trial Details
NCT Number NCT07715227
Lead Sponsor Al-Farabi Kazakh National University
Collaborators: Research and Production Center "Comprehensive Equipment", BrainPatch
Conditions Healthy Volunteers
Enrollment 56 participants
Start Date 2021-11-30
Primary Completion 2022-05-13 (estimated)
Study Completion 2022-05-13 (estimated)
Updated on ClinicalTrials.gov 2026-07-20