Trcheal High-flow for Weaning From Mechanical Ventilation

Multicentre randomized trial to determine whether tracheal high-flow nasal oxygen can improve weaning outcome vs. conventional oxygen therapy in critically ill tracheostomized patients who are hypoxemic.

NCT Number	NCT07714564
Lead Sponsor	Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions	Tracheostomy, Mechanical Ventilation, Hypoxemic Respiratory Failure
Enrollment	500 participants
Start Date	2026-10-01
Primary Completion	2028-12-31 (estimated)
Study Completion	2029-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-20