Clinical Trial

Arterial Stiffness and Endothelial Function in Heart Failure

Study acronym: ASEF-HF
Not Yet Recruiting
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Summary
Heart Failure (HF) is a global condition affecting at least 26 million people worldwide. Despite advances in treatment, HF patients continue to experience poor health outcomes. This study aims to improve understanding of the role of blood vessels in people with heart failure. The study will assess how arterial stiffness (how stiff blood vessels are) and endothelial function (how well the lining of blood vessels functions) change over time and respond to treatments received as part of routine clinical care. Blood vessel function and heart performance will be assessed at three time points: * At baseline (when Patients are first diagnosed with heart failure). * After completing 4 ± 2 weeks of heart-failure medicines prescribed to patients as part of their routine clinical care. * After completion of cardiac rehabilitation program as a part of their routine clinical care. All assessments are non-invasive.
Trial Details
NCT Number NCT07713719
Lead Sponsor Coventry University
Conditions Heart Failure
Enrollment 50 participants
Start Date 2026-08
Primary Completion 2028-06 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-20