Clinical Trial

INfections in Patients Treated With CAR-T

Study acronym: IN-CART
Not Yet Recruiting
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Summary
This study includes adults with multiple myeloma or B-cell lymphoma who were/will be treated with CAR-T cell therapy at the IRCCS Azienda Ospedaliero-Universitaria di Bologna. The aim is to better understand infections that may occur during the first year after CAR-T treatment, including how often they happen, their causes, and factors that may increase the risk. The study will use information from patients treated in the past and from newly enrolled patients. For some patients who develop fever after CAR-T therapy, a rapid molecular blood test will be used alongside standard tests to help identify bloodstream infections more quickly and support timely clinical care.
Trial Details
NCT Number NCT07713511
Lead Sponsor IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions Relapsed Multiple Myeloma, Refractory Multiple Myeloma, B-Cell Non-Hodgkin Lymphoma, Bloodstream Infections, CAR-T Cell Therapy
Enrollment 290 participants
Start Date 2026-11-01
Primary Completion 2027-10-31 (estimated)
Study Completion 2029-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-20