Clinical Trial

Understanding the Paradoxical Rise in Blood Glucose in the Context of a Low-carbohydrate Diet

Completed
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Summary
The purpose of this project was to elucidate the phenomenon of elevated blood glucose in the context of dietary carbohydrate restriction. Accordingly, we sought to quantify glucagon, and related hormones, between individuals that are adhering to a low-carbohydrate diet that manifests with normal vs. elevated glucose. Moreover, we sought to test the dynamic effect of macronutrients on these same outcomes. Each participant completed 3 testing periods that included the consumption of a glucose drink, protein drink, or fat (olive oil) drink in a random order and separated by at least 2 days. Each drink was matched for volume and total calories and bloodwork was taken every 30 minutes to assess the outcomes of interest.
Trial Details
NCT Number NCT07713316
Lead Sponsor Brigham Young University
Collaborators: Levels Health Inc.
Conditions Elevated Blood Glucose, Low-carbohydrate Diet
Enrollment 24 participants
Start Date 2021-05-15
Primary Completion 2022-06-30 (estimated)
Study Completion 2022-12-17 (estimated)
Updated on ClinicalTrials.gov 2026-07-20