Pilot Radioembolisation Clinical Trial Assessing Safety and Efficacy in Recurrent Glioma

This study is testing a new way of treating brain tumours using tiny radioactive beads called SIR-Spheres® (90Y-labelled Resin Microspheres). These microspheres are placed into the blood vessels that feed the tumour. The treatment gives off radiation inside the tumour to try to stop it from growing. This type of treatment is called Selective Internal Radiation Therapy (SIRT), Transarterial Radioembolisation (TARE), or radioembolisation. It is already an accepted treatment for patients with liver cancer. In this study, we are testing if this treatment can be done safely in the brain and how well it works.

NCT Number	NCT07712770
Lead Sponsor	Olivia Newton-John Cancer Research Institute Collaborators: Austin Health
Conditions	Recurrent Glioblastoma IDH Wildtype, Recurrent Glioblastoma
Enrollment	12 participants
Start Date	2026-10
Primary Completion	2028-11 (estimated)
Study Completion	2028-11 (estimated)
Updated on ClinicalTrials.gov	2026-07-17